Just like cigarettes are “nicotine” delivery systems, dendritic cells (DCs) are antigen delivery cells. After \u00a0decades of research, it is now clear that DCs are at the center of the immune system, given their ability to control both immune tolerance and general immunity. Immunity results from a complex interplay between the innate immune system (which is antigen-nonspecific) and the adaptive immune system (which is antigen-specific). The cells and molecules of the innate immune system use non-clonal recognition receptors, including but not limited to lectins, Toll-like receptors (TLRs), NOD-like receptors (NLRs) and helicases. B cells and T cells of the adaptive immune system use clonal receptors that recognize antigens, or their derived peptides, in a highly specific manner.<\/em><\/h5>\n

\u00a0In 2011, the Nobel Prize for Medicine – Physiology was awarded for the discovery of molecular and cellular sensors of microbes. Jules Hoffman and Bruce Beutler received the award for their seminal contributions to the discovery of TLRs in the 1990s. Ralph Steinman, who eventually died from advanced pancreatic cancer despite his use of experimental DCs via vaccines, \u00a0received the award for the discovery in 1973 of DCs three days after his death.<\/h5>\n

DCs, \u00a0are linked to their environment through a wealth of molecular sensors that allow them to capture invading microbes and to transmit the resulting information to lymphocytes. <\/em>Thus, DCs provide an essential link between the innate and adaptive immune responses. In this perspective, the\u00a0\u00a0immune system has the potential to eliminate neoplastic cells. \u00a0And as we have known for centuries, the key to malignant reversibility lies within….not with the “cut-poison-burn” approach.<\/h5>\n

http:\/\/www.nature.com\/nrc\/journal\/v12\/n4\/full\/nrc3258.html<\/a><\/h6>\n

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DISCLAIMER<\/h6>\n

All information contained in this site are pedagogical in nature, not intended to give any technical, medical, legal or illegal advice. Some of the links provided are for convenience, they do not constitute a formal endorsement. The Holistic Oncology Movie team, the Holistic Wellbeing Campaign and center and the Holistic Well-Being Productions, including agents thereof and Christian Joubert bear no responsibility for the accuracy, the legality or the content of the external sites or for those subsequent links which may be invoked for informational purposes. Furthermore, not only is nothing in this website to be construed as medical and legal advise, but any and all replies, comments and posts can not be deemed to constitute either a therapist-patient nor an attorney-client relationship.<\/h6>\n

2013 \u2013 2014 Copyright: Holitic Oncology Movie, Holistic Wellbeing Productions and Christian Joubert. All rights reserved.<\/h6>\n

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Just like cigarettes are “nicotine” delivery systems, dendritic cells (DCs) are antigen delivery cells. After \u00a0decades of research, it is now clear that DCs are at the center of the immune system, given their ability to control both immune tolerance …<\/p>\n

One of the keys to cancer reversibility is the dendritic immune surveillance cell. Nobel prize researchers confirm:<\/span> Read More »<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/holisticoncologymovie.com\/index.php?rest_route=\/wp\/v2\/posts\/427"}],"collection":[{"href":"http:\/\/holisticoncologymovie.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/holisticoncologymovie.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/holisticoncologymovie.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/holisticoncologymovie.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=427"}],"version-history":[{"count":4,"href":"http:\/\/holisticoncologymovie.com\/index.php?rest_route=\/wp\/v2\/posts\/427\/revisions"}],"predecessor-version":[{"id":535,"href":"http:\/\/holisticoncologymovie.com\/index.php?rest_route=\/wp\/v2\/posts\/427\/revisions\/535"}],"wp:attachment":[{"href":"http:\/\/holisticoncologymovie.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=427"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/holisticoncologymovie.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=427"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/holisticoncologymovie.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=427"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}